Striving to produce affordable treatments for Alzheimer's Disease

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Background...

Profesor J.T.Walker - founder and Research Director of Alzeim Ltd

Alzeim Ltd was established in April 2004 by Professor Trevor Walker, David Palmer and Alan Porter – former colleagues in agri-science. Trevor spent two years in Wales after his retirement from biotechnology venture capital work investigating possibilities and conducting experimental research into the production of Galanthamine and other alkaloids before Alzeim was created.

Topographical and climatic research was undertaken in the Black Mountains, working with local farmers who have used former pasture land to grow daffodils under Alzeim’s direction. Results from extensive trials indicated that several specific varieties of daffodil produce the product – under Powys conditions - in a quantity that justifies production on a scale to enable a ready supply of a generic Galanthamine-based drug to be available.

The company has been funded to date by its directors and a number of  private investors. In addition, grants have been received from the Welsh Assembly Government's SMARTCymru programme and from a local Powys fund - Glasu.

The business has aroused international interest – mainly as a result of awareness marketing – because of the daffodil being the iconic Welsh national flower, the parlous state of Welsh upland farming and the spectacular local scenery. Alzeim has been featured on various television channels, and numerous press articles have been published.  Publicity has also been generated by supportive pressure groups wanting more action to curb the ravages of Alzheimer’s Disease.

Alzeim’s product strategy is divided into four phases. The first is the production of natural Galanthamine from its specially grown daffodil crops; the second is the production of a range of Galanthamine-based products – some with unusual drug-delivery systems - for the generic prescription market due to open up in 2009; the third will be to develop Galanthamine-based, safe products for the health market sector and the fourth will feature other alkaloids and possibly other medical conditions.

The first phase involves the complete agronomic processing regime  - using tonnes of specific varieties of daffodils including their planting, fertilizing, growth control, harvesting and ultimate extraction.

The business is based at Black Mountains Business Park at Talgarth in Southern Powys. The facility, which is undergoing fit-out for extraction machinery, will serve its purpose as a research and administrative base for the near future until a dedicated factory can be built.

 

About Us   Background   Alzheimer's Disease   Galanthamine more..   Links   Contact us 

Alzeim Ltd, Honddu House, Hospital Road, Talgarth, Brecon, Powys, LD3 0DT, Wales Tel: 01874 712373
Registered in Wales - 5089373      VAT Registration 850 6668 07